Lymphocyte Subpopulation plays an important role in monitoring human's immune system condition, cellular immunity and humoral immunity. When you are suspected to have an immune complex-related condition which usually indicates immune disease or kidney disease, Lymphocyte Subpopulation Test may be ordered. The tests helps doctor check the status of patient's complement system.
Lymphocyte Subpopulation Tests includes the following lab values:
- CD4: CD4 cells are sometimes called T-cells, which are “helper” cells and lead the attack against infections.
- CD8: CD8 are "suppressor" cells that end the immune response. CD8 cells can also be "killer" cells that kill cancer cells and cells infected with a virus.
- B cells. B cells can differentiate into plasmocyte and helps T cells participating in immune response.
- NK cells. NK cells play a major role in the host-rejection of both tumours and virally infected cells. It helps monitor the early infection stage.
- CD4/CD8. It monitors cellar immune function. If it rises, your cellar immune response is overactive; otherwise, it is over passive.
- Cyclosporine Blood Concentration Prediction. It is important in guiding drug use safety. < 200ug/L: insufficient dose; >400ug/L: overdose, this usually leads to side effects.
- Antigen. It figures out the food antigens and helps diagnose allergic disease in particular.
Subpopulation test helps monitor the effectiveness of kidney disease treatment you are taking and monitors your immune system and help you decide whether, when, how to start immune treatment and other therapies to prevent infections.