Kidney Damage Subsets helps your doctor make an overview about your kidney medical condition, including: whether your kidney are injured or not; How severity your kidney damages is, find your sensitivity to current drugs and are the basis for your doctor to consider drug changes for you.
Kidney Damage Subsets focus on the content of urine, which totally include 12 indexes as follows:
- Urinary Total Protein
total protein:creatinine ratio allows reliable estimation of total 24-hour urinary protein excretion. The degree of proteinuria correlates with the rate of progression of the underlying kidney disease and is the most reliable prognostic factor in CKD.
A Micro-albumin test is used to detect early signs of kidney damage in people who have a risk of kidney disease.Microalbumin tests are recommended for people with an increased risk of kidney disease, such as those with type 1 diabetes, type 2 diabetes or high blood pressure.
- Urinary Retinol Binding Protein
Retinol-binding protein is a low-molecular-weight protein of 21 kDa that transports retinol (vitamin A alcohol) from the liver to peripheral tissues. It is used for:
Assessing renal tubular injury or dysfunction
Screening for other tubular abnormalities
Detecting chronic asymptomatic renal tubular dysfunction
- Immunoglobulin G
The gamma globulin band as seen in conventional serum protein electrophoresis consists of 5 immunoglobulins. In normal serum, about 80% is immunoglobulin G (IgG). It is used for detecting or monitoring of monoclonal gammopathies and immune deficiencies.
- Beta-2 Microglobulin
Both blood and urine B2M tests may be ordered when a person has symptoms associated with kidney dysfunction and the doctor wants to distinguish between disorders that affect the glomeruli and the renal tubules. A urine test may also be ordered periodically to monitor a person who has had a kidney transplant and to monitor those exposed to high concentrations of cadmium or mercury.
α1-microglobulin works as a marker of early nephropathy in type 2 diabetics.
- light chainκ
light chainκ works to test prerenal proteinuria, which can be seen in light chain disease, multiple myeloma, lymphoma etc.
- light chainγ
light chainγ works to test prerenal proteinuria, which can be seen in light chain disease, multiple myeloma, lymphoma etc.
NAG is a marker to find out the inflammation injuries in renal tubular epithelial cell.
GGT is also a marker to find out the inflammation injuries in renal tubular epithelial cell.
- Urinary Osmotic Pressure
Urinary Osmotic Pressure is used to estimate the damages on renal tubules.