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Glomerulonephritis (GN, or Nephritis) is a kidney disorder in which the tiny filters of the kidneys that help to clean the blood called glomeruli become inflamed or damaged. This allows protein and red blood cells that normally circulate in the blood to pass into the urine. Left untreated, this chronic inflammation can lead to scarring, loss of kidney function, and Kidney Failure requiring dialysis or transplantation.
Glomerulonephritis can be caused by a vast array of factors including autoimmune disorders, infections, and other diseases. Usually, individuals develop Acute Nephritis after they have experienced ailments like strep throat, rheumatic fever, and scarlet fever.
• For 5 percent of men who end up with kidney disease, the disorder can be hereditary.
• Children and even adults may get Glomerulonephritis due to damage of the kidneys' filtering units caused by streptococcus bacteria.
• Adult nephritis may occur as a result of pneumonia, vasculitis, or the inflammation of one person's blood vessels, mumps and hepatitis. Sometimes, abscesses can also be one reason.
• Certain medications and poinsons
• Metabolic disorders
• Other causes also include gout, yellow fever, renal tuberculosis, immune complex disease, urethral stricture, typhoid fever, hermann's syndrome, etc.
Exams and Tests
• Urine test. A urinalysis may show red blood cells and red cells casts in urine (an indicator of possible damage to the glomeruli), white blood cells (a common indicator of infection or inflammation), increase protein (may indicate nephron damage), increased serum creatinine or urea.
• Blood test. This can offer information about kidney damage and impairment of the glomeruli by measuring levels of toxic wastes such as creatinine and blood urea nitrogen (BUN).
• Imaging tests. Once detecting evidence of damage, the doctor may recommend tests such as a kidney X-ray, untrasound, or CT scan.
• Kidney biopsy. It is almost always necessary to confirm a diagnosis of GN.
Glomerulonephritis may be temporary and reversible, or it may get worse. Progressive nephritis may lead to Chronic Kidney Failure, reduced kidney function, and end stage renal disease(ESRD). Fortunately, timely and effective treatment can help patients prevent renal failure. For information about the best treatment for you, feel free to Contact Us.
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